A Marine Biodiscovery Laboratory in Ireland

Brominated Bisindole Alkaloids from the Celtic Sea Sponge Spongosorites calcicola

See the recent publication from the National Marine Biodiscovery Lab. This paper describes the first chemical investigation of the subtidal sponge, Spongosorites calcicola. This led to the identification of two new bisindole alkaloids, the Calcicamides, with six other known indole alkaloids. These new bisindole alkaloids can represent key biosynthetic intermediates for other known bioactive bisindoles.

See more at https://doi.org/10.3390/molecules24213890


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